Asthma - Breathing

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Asthma
Introduction

Asthma is a very common long-term condition; at least one child in 10 and about one adult in 20 have asthma. It can be so mild that it's hardly noticeable, or it can come on suddenly and be so severe that the affected person may panic. Most cases are somewhere in between. Asthma affects the breathing, making it harder to get enough breath, and causing wheezing, coughing and a strong feeling that the air can't get in or out of the lungs. This feeling is caused when the airways narrow.

Asthma is partly an allergic problem, and there is a connection between asthma, hay fever and the skin condition eczema. This is because all three conditions are related to a single one of the genes inherited from your parents. Because of this genetic connection, these three conditions run in families, sometimes causing asthma, sometimes hay fever and sometimes eczema. Some people may have more than one of these.

Asthma doesn't cause trouble all the time. Attacks may sometimes occur quite often, but in many cases the person with asthma is free from the trouble for quite long periods.

More than most disorders, asthma is a 'self-help' condition in which the affected person can do much to prevent attacks. And when attacks do happen they can usually be stopped fairly quickly.

However, it is not a trivial disease – at least 2000 people die from it each year in the UK, and most of those deaths are avoidable if people know how to recognise the danger signs.

Causes

The smaller air tubes in the lungs are much narrower than most people realise, and these tubes don't have to get much narrower for it to be very hard for the air to get through. The tubes, called bronchioles, have circular muscles in their walls. In asthma the muscles are may tighten (as part of an allergic response or for no obvious reason) so that some or most of the tubes are narrowed. The passage of air in and out of the tiny air sacs where oxygen passes into the blood is partly or almost completely blocked.

On top of this, asthma also features swelling of the lining of the air tubes. The linings also have tiny glands that push out mucus, and with asthma there is an increase in mucus production that also tends to block the air passage.

An asthma attack can be started by breathing in, or contact with, quite a number of different things. These include:

  • Pollens or fungal spores
  • Viral and bacterial chest infections
  • Animal allergen or house dust mite
  • Food additives, such as tartrazine
  • Seasonal changes
  • Strong smells or perfumes
  • Smoke pollution, or vehicle exhaust fumes
  • Worry and stress
  • Some medicines, especially beta-blockers and aspirin
  • Alcohol
  • Nuts
  • Shellfish
  • Some fruits
  • Heavy exercise, especially when it's cold.

The forms of asthma can be divided into two groups – those with a known cause and those without. The first group mainly affects people with a general condition called atopy. This is a genetic condition that makes people allergic to various substances (allergens). It also increases the likelihood of eczema and hay fever and there is often a family history of these conditions.

The second group are more likely to have developed asthma as a result of exposure to industrial or atmospheric pollution, or drugs such as NSAIDs (non-steroidal anti-inflammatory drugs) and beta blockers. Well over 200 industrial substances are known to bring on asthma.

People with atopy are also more likely to develop asthma in response to industrial and other pollutants than are people who do not have atopy, and to do so more quickly.

 

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