UK Charities - Against Breast Cancer

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The ABC Research Team is based at the Middlesex Hospital in London - part of University College London Hospitals - and is funded by Against Breast Cancer (ABC).

The ABC programme is looking at secondary spread, when cancer cells travel from the breast to other, often vital, parts of the body to form additional cancers. Through our work we want to improve the care, treatment and survival rates of women with, and at risk of the disease.  Our work is a unique combination of the following research: 

Diet and Lifestyle

Much of the advice currently given out about diet and cancer is unproven.  The ABC Diet and Lifestyle co-ordinators are leading a ten year study to find scientific evidence about what foods, exercise and other lifestyle factors affect the progress of breast cancer. The ABC Study involves looking at the diet and lifestyle of women with breast cancer by asking them to fill out questionnaires and give samples of things such as blood and urine.  We then track their progress over a period of at least five years.  We aim eventually to provide proven advice on how changing your diet and lifestyle can improve your chances of surviving breast cancer.  

Biochemistry

ABC Biochemists are examining how breast cancer cells are made up in order to understand why some cancers spread and others do not.  The ABC biochemists are studying complex sugars that they suspect play an important role in the spread of breast cancer.  Early work has suggested that these sugars, which are found in human cells, could play a part in the development of cancer cells. Continuing work involves closer examination of complex sugars to see whether they can be used as a way of either detecting the disease.  

Immunology

ABC Immunologists are looking at the possibilities for finding a vaccine against breast cancer.  ABC researchers believe that some sufferers may have a natural immunity to the disease, which keeps the growth of cancer cells in check.  If true, this could help all future sufferers.  ABC research has already shown that whose cancer has spread to other parts of the body have low levels of natural immunity.  We are now looking at how a person’s own immunity could be stimulated to fight secondary spread.

http://www.aabc.org.uk

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